EVOM3, Epithelial Volt/Ohm (TEER) Meter 3
The EVOM3 delivers improved workflow efficiency, more stable and repeatable measurements versus traditional Trans Epithelial Electrical Resistance (TEER) meters. The new graphical displays for trend analysis and measurement values helps scientists deliver simple, stepwise methodology during experimental measurements.
TEER measurement with automatic data logging
- Low noise design offers greater resolution and accuracy
- Automatic 20X sample averaging improves accuracy and stability
- Adjustable fixed measurement currents (2, 4 or 10 μA)
- Resistance auto ranging from 1 Ω to 100,000 Ω or with three fixed current ranges
- Reliable low current, low voltage design prevents metal ion transport
- Fast resistance stabilization on low levels under 200 Ω with resolution to 0.1 Ω
- Ergonomic tilt stand for low glare operation
- Graphical display of popular plates (6, 12, 24, 96) for trend analysis
- The display shows the most recent set of parameters
- Automatic plate indexing operation with or without control well subtraction for resistance and potential difference (PD) measurements
- Continuous data logging via USB (PC, Mac, Linux)
- Saves date stamped data to a spreadsheet readable file on a USB drive
- Upgradable firmware
EVOM3 benefits
- Eliminates errors and reduces experimental processing time
- Auto data logging eliminates the need to track data by hand
- The small footprint allows more bench space
- Easy calibration and verification
- Footswitch for hands-free recording
- Prevent data loss with auto save and data recovery when battery is low
- TEER is easily computed by applying a unit area formula to the resistance
Applications of EVOM3
- Measure epithelial or endothelial tissues for confluence, TEER and potential difference
- Permeability, conductance and drug studies
- Continuous digital monitoring of a target membrane
- Common studies
- Blood-brain barrier transport
- Lung epithelial tissue studies
- Intestinal tissue studies
- Skin studies
Stanifer, M. L., et al. (2016). Reovirus intermediate subviral particles constitute a strategy to infect intestinal epithelial cells by exploiting TGF-β dependent pro-survival signaling. Cellular Microbiology, 18(12), 1831–1845.
Meenach, S. A., et al. (2016). Development of three-dimensional lung multicellular spheroids in air- and liquid-interface culture for the evaluation of anticancer therapeutics. International Journal of Oncology, 48(4), 1701–1709.
Ferguson, M. C., et al. (2015). Ability of the Encephalitic Arbovirus Semliki Forest Virus To Cross the Blood-Brain Barrier Is Determined by the Charge of the E2 Glycoprotein. Journal of Virology, 89(15), 7536–7549.