NanoFil syringe and needles
NanoFil™ syringes - Gas Tight Injection System
WPI’s NanoFil™ is a specially designed, gas-tight microliter syringe developed specifically for ultra-precise, low-volume fluid transfer that boasts consistency in its performance—with virtually zero dead volume. Microliter-level injections with NanoFil™ provide incredible accuracy with results you can trust.
Adventages of NanoFil™ syringes
- NanoFil™ is the smallest dead volume microinjection system
- Biologically compatible injection syringe
- Various needle sizes available: 26-36G
- Blunt or tri-beveled needles
- Compatible with WPI's UMP3 microinjection system for precision injections
Benefits
- Virtually zero dead volume microinjection syringe (0.5 µL or less)
- Strong gas-tight seal providing both repeatability and superior application outcomes
- Biologically compatible injection syringe (All the seals are constructed of inert materials for better chemical and biological compatibility)
- Switching the syringe tip during an experiment is easy
- Variety of injection tip options (needles and quartz tubing)
- Unique tri-beveled needles for easier penetration
Applications of NanoFil™ syringes
- Animal research, viral targeting (e.g. AAV construct, DREADDS)
- Capillary electrophoresis
- Versatile research applications, ophthalmology with usage of Retinal Pigment Epithelial (RPE) and Intra Ocular (IO) injection kits
Gas-Tight Control in NanoFil™ Syringe
Gas-tight control is particularly critical for applications requiring utmost accuracy and precision during low-volume fluid handling. Having a quality gas-tight design ensures a vacuum-like seal between the syringe and needle, supplying the necessary force to advance small samples forward during delivery, and upwards during withdraw. NanoFil’s virtual zero dead-volume comes from its thoughtfully designed coupling mechanism, where all WPI NanoFil™ needles insert directly into the syringe barrel, creating a 1:1 connection with the syringe’s plunger. Priming your syringe is made effortless with unparalleled control, supported by a sure-seal, gas-tight system.
Functionality & versatility
WPI’s NanoFil™ promotes a range of applications, supported by our universal NanoFil™ needles – where all gauges are fully interchangeable and compatible with all NanoFilTM syringes.
NanoFil™ Intraocular (IO) and Retinal Pigment Epithelium (RPE) kits diversify the integration for fine-tuned fluid transfer into sensitive tissue, mitigating user error. NanoFil™ syringes easily attach to WPI’s UMP3 syringe pump paired to a stereotaxic or manipulator-fixed setups for enhanced control.
NanoFil™ needles
The replaceable needles used with the NanoFil are available with either blunt or beveled tip designs. The blunt tip is used for injection into soft tissue and when a uniform solution distribution is needed. The beveled style NanoFil needles are used for applications that involve the penetration through a tough tissue. Nanofil needles are offered in sizes of 26G to 36G (OD of 460 µm to 120 µm).
Generally, a smaller needle tip diameter is better to limit diffusion occurring at the needle tip. A 36G needle would be the best suitable needle to restrict the diffusion at the tip of the needle. Any possible error resulting from diffusion when using a 36G NanoFil needle is expected to be negligible. (The error would be in the sub-nanoliter range). Thus, the use of NanoFil needles can help you maintain better accuracy during the injection of microliter and sub-microliter volumes.
